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LCMV Glycosylation Modulates Viral Fitness and Cell Tropism

The glycoprotein (GP) of arenaviruses is glycosylated at 11 conserved N-glycosylation sites. We constructed recombinant lymphocytic choriomeningitis virus (rLCMV) featuring either additions or deletions of these N-glycans to investigate their role in the viral life cycle. N-glycosylation at two site...

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Main Authors: Bonhomme, Cyrille J., Knopp, Kristeene A., Bederka, Lydia H., Angelini, Megan M., Buchmeier, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538765/
https://ncbi.nlm.nih.gov/pubmed/23308183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053273
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