Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions

BACKGROUND: Environmental and intrinsic stress factors can result in the global alteration of yeast physiology, as evidenced by several transcriptional studies. Hypoxia has been shown to have a beneficial effect on the expression of recombinant proteins in Pichia pastoris growing on glucose. Further...

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Autors principals: Carnicer, Marc, ten Pierick, Angela, van Dam, Jan, Heijnen, Joseph J, Albiol, Joan, van Gulik, Walter, Ferrer, Pau
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538582/
https://ncbi.nlm.nih.gov/pubmed/22704468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-83
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