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Germline Predictors of Androgen Deprivation Therapy Response in Advanced Prostate Cancer

OBJECTIVE: To evaluate whether germline variations in genes involved in sex steroid biosynthesis and metabolic pathways predict time to treatment failure for patients with advanced prostate cancer undergoing androgen deprivation therapy (ADT), because there are few known clinical predictors of respo...

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Detalhes bibliográficos
Main Authors: Kohli, Manish, Riska, Shaun M., Mahoney, Douglas W., Chai, High S., Hillman, David W., Rider, David N., Costello, Brian A., Qin, Rui, Lamba, Jatinder, Sahasrabudhe, Deepak M., Cerhan, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mayo Foundation 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538410/
https://ncbi.nlm.nih.gov/pubmed/22386179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mayocp.2011.09.009
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