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Regulating Cytokine Function Enhances Safety and Activity of Genetic Cancer Therapies

Genetic therapies, including transfected immune cells and viral vectors, continue to show clinical responses as systemically deliverable and targeted therapeutics, with the first such approaches having been approved for cancer treatment. The majority of these employ cytokine transgenes. However, exp...

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Detalhes bibliográficos
Principais autores: Chen, Hannah, Sampath, Padma, Hou, Weizhou, Thorne, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538315/
https://ncbi.nlm.nih.gov/pubmed/23281444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.225
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