Induced Pluripotent Mesenchymal Stromal Cell Clones Retain Donor-derived Differences in DNA Methylation Profiles

Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) is an epigenetic phenomenon. It has been suggested that iPSC retain some tissue-specific memory whereas little is known about interindividual epigenetic variation. We have reprogrammed mesenchymal stromal cells from human bon...

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Hlavní autoři: Shao, Kaifeng, Koch, Carmen, Gupta, Manoj K, Lin, Qiong, Lenz, Michael, Laufs, Stephanie, Denecke, Bernd, Schmidt, Manfred, Linke, Matthias, Hennies, Hans C, Hescheler, Jürgen, Zenke, Martin, Zechner, Ulrich, Šarić, Tomo, Wagner, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538313/
https://ncbi.nlm.nih.gov/pubmed/23032973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.207
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