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Targeting Gonadotropin-releasing Hormone Receptor Inhibits the Early Step of Ovarian Cancer Metastasis by Modulating Tumor-mesothelial Adhesion

Ovarian cancer has a clear predilection to metastasize to the peritoneum, which represents one of the most important prognostic factors of poor clinical outcome. Gonadotropin-releasing hormone (GnRH) receptor is significantly overexpressed during the malignant progression of human ovarian cancer. He...

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Detalhes bibliográficos
Principais autores: Cheung, Lydia WT, Yung, Susan, Chan, Tak-Mao, Leung, Peter CK, Wong, Alice ST
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538308/
https://ncbi.nlm.nih.gov/pubmed/23164934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.187
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