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Endothelial glucocorticoid receptor is required for protection against sepsis

The glucocorticoid receptor (GR) is ubiquitously expressed on nearly all cell types, but tissue-specific deletion of this receptor can produce dramatic whole organism phenotypes. In this study we investigated the role of the endothelial GR in sepsis in vivo and in vitro. Mice with an endothelial-spe...

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Autors principals: Goodwin, Julie E., Feng, Yan, Velazquez, Heino, Sessa, William C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538225/
https://ncbi.nlm.nih.gov/pubmed/23248291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210200110
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