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Birth–death skyline plot reveals temporal changes of epidemic spread in HIV and hepatitis C virus (HCV)

Phylogenetic trees can be used to infer the processes that generated them. Here, we introduce a model, the Bayesian birth–death skyline plot, which explicitly estimates the rate of transmission, recovery, and sampling and thus allows inference of the effective reproductive number directly from genet...

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Detalhes bibliográficos
Main Authors: Stadler, Tanja, Kühnert, Denise, Bonhoeffer, Sebastian, Drummond, Alexei J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538216/
https://ncbi.nlm.nih.gov/pubmed/23248286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207965110
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