Andrographis paniculata Extract (HMPL-004) for Active Ulcerative Colitis

OBJECTIVES: Andrographis paniculata has in vitro inhibitory activity against TNF-α, IL-1β and NF-κB. A pilot study of A. paniculata extract (HMPL-004) suggested similar efficacy to mesalamine for ulcerative colitis. METHODS: A randomized, double-blind, placebo-controlled trial evaluated the efficacy...

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Detalhes bibliográficos
Main Authors: Sandborn, William J, Targan, Stephan R, Byers, Vera S, Rutty, Dean A, Mu, Hua, Zhang, Xun, Tang, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538174/
https://ncbi.nlm.nih.gov/pubmed/23044768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2012.340
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