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TARGETED SERCA2a GENE DELIVERY TO RESTORE ELECTRICAL STABILITY IN THE FAILING HEART
BACKGROUND: Beat-to-beat alternation of the cardiac action potential (Vm-Alt) attributable to fluctuations in cellular calcium cycling (Ca-Alt) is a recognized mechanism of ventricular fibrillation (VF). Recently, we reported that SERCA2a, the pump responsible for re-uptake of cytosolic calcium duri...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538142/ https://ncbi.nlm.nih.gov/pubmed/23019291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.071480 |
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