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Human-specific protein isoforms produced by novel splice sites in the human genome after the human-chimpanzee divergence

BACKGROUND: Evolution of splice sites is a well-known phenomenon that results in transcript diversity during human evolution. Many novel splice sites are derived from repetitive elements and may not contribute to protein products. Here, we analyzed annotated human protein-coding exons and identified...

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Detalhes bibliográficos
Main Authors: Kim, Dong Seon, Hahn, Yoonsoo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538075/
https://ncbi.nlm.nih.gov/pubmed/23148531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-299
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