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Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines

The search for effective plant-derived anti-cancer agents or their synthetic analogs has continued to gain interest in drug development. The anti-cancer activity of parthenolide (PTL) isolated from Tanacetum parthenium, has been attributed to the presence of α-methylene-γ-lactone skeleton. In the pr...

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Detalhes bibliográficos
Main Authors: Wyrębska, Anna, Szymański, Jacek, Gach, Katarzyna, Piekielna, Justyna, Koszuk, Jacek, Janecki, Tomasz, Janecka, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538020/
https://ncbi.nlm.nih.gov/pubmed/23065294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-012-2215-6
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