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Secrets of drug resistance in NSCLC exposed by new molecular definition of EMT

NSCLC metastasis and drug resistance has been associated with epithelial-to-mesenchymal transition (EMT). This study reports the development of a robust gene expression signature of EMT in NSCLC and reveals new insights into the key molecular events that underlie EMT and drug resistance in NSCLC.

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Detalhes bibliográficos
Main Authors: Neel, Dana S, Bivona, Trever G
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537879/
https://ncbi.nlm.nih.gov/pubmed/23172883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3232
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