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Lipotoxicity impairs incretin signalling
The incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic peptide are secreted by enteroendocrine cells and augment glucose-induced insulin secretion in response to food ingestion in a glucose-dependent manner. The mechanism forms the basis for incretin-based therapies in ty...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537857/ https://ncbi.nlm.nih.gov/pubmed/23188391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2788-6 |
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