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HNF1β Is Essential for Nephron Segmentation during Nephrogenesis
Nephrons comprise a blood filter and an epithelial tubule that is subdivided into proximal and distal segments, but what directs this patterning during kidney organogenesis is not well understood. Using zebrafish, we found that the HNF1β paralogues hnf1ba and hnf1bb, which encode homeodomain transcr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537220/ https://ncbi.nlm.nih.gov/pubmed/23160512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012070756 |
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