p-Cresyl Sulfate Promotes Insulin Resistance Associated with CKD

The mechanisms underlying the insulin resistance that frequently accompanies CKD are poorly understood, but the retention of renally excreted compounds may play a role. One such compound is p-cresyl sulfate (PCS), a protein-bound uremic toxin that originates from tyrosine metabolism by intestinal mi...

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Autori principali: Koppe, Laetitia, Pillon, Nicolas J., Vella, Roxane E., Croze, Marine L., Pelletier, Caroline C., Chambert, Stéphane, Massy, Ziad, Glorieux, Griet, Vanholder, Raymond, Dugenet, Yann, Soula, Hédi A., Fouque, Denis, Soulage, Christophe O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2012
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537215/
https://ncbi.nlm.nih.gov/pubmed/23274953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012050503
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