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A Mutation in the Latency-Related Gene of Bovine Herpesvirus 1 Inhibits Protein Expression from Open Reading Frame 2 and an Adjacent Reading Frame during Productive Infection

The latency-related (LR) gene of bovine herpesvirus 1 (BHV-1) is abundantly expressed during latency. A mutant BHV-1 strain that contains three stop codons at the 5′ terminus of the LR gene (LR mutant) does not reactivate from latency. This study demonstrates that the LR mutant does not express open...

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Détails bibliographiques
Auteurs principaux: Jiang, Yunquan, Inman, Melissa, Zhang, Yange, Posadas, Nuria Alemañ, Jones, Clinton
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC353721/
https://ncbi.nlm.nih.gov/pubmed/14990740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.3184-3189.2004
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