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Modulation of Inflammatory Gene Expression by the Ribotoxin Deoxynivalenol Involves Coordinate Regulation of the Transcriptome and Translatome

The trichothecene deoxynivalenol (DON), a common contaminant of cereal-based foods, is a ribotoxic mycotoxin known to activate innate immune cells in vivo and in vitro. Although it is recognized that DON induces transcription and mRNA stabilization of inflammation-associated mRNAs in mononuclear pha...

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Hlavní autoři: He, Kaiyu, Pan, Xiao, Zhou, Hui-Ren, Pestka, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537125/
https://ncbi.nlm.nih.gov/pubmed/22968694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs266
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