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Mechanical Modulation of ATP-binding Affinity of V(1)-ATPase

V(1)-ATPase is a rotary motor protein that rotates the central shaft in a counterclockwise direction hydrolyzing ATP. Although the ATP-binding process is suggested to be the most critical reaction step for torque generation in F(1)-ATPase (the closest relative of V(1)-ATPase evolutionarily), the rol...

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Autors principals: Tirtom, Naciye Esma, Okuno, Daichi, Nakano, Masahiro, Yokoyama, Ken, Noji, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537060/
https://ncbi.nlm.nih.gov/pubmed/23155048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.420729
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