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Designing a Soluble Near Full-length HIV-1 gp41 Trimer

The HIV-1 envelope spike is a trimer of heterodimers composed of an external glycoprotein gp120 and a transmembrane glycoprotein gp41. gp120 initiates virus entry by binding to host receptors, whereas gp41 mediates fusion between viral and host membranes. Although the basic pathway of HIV-1 entry ha...

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Detalhes bibliográficos
Main Authors: Gao, Guofen, Wieczorek, Lindsay, Peachman, Kristina K., Polonis, Victoria R., Alving, Carl R., Rao, Mangala, Rao, Venigalla B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537018/
https://ncbi.nlm.nih.gov/pubmed/23184960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424432
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