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Irreversible Heavy Chain Transfer to Hyaluronan Oligosaccharides by Tumor Necrosis Factor-stimulated Gene-6

The covalent transfer of heavy chains (HCs) from inter-α-inhibitor (IαI) to hyaluronan (HA) via the protein product of tumor necrosis factor-stimulated gene-6 (TSG-6) forms the HC-HA complex, a pathological form of HA that promotes the adhesion of leukocytes to HA matrices. The transfer of HCs to hi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lauer, Mark E., Glant, Tibor T., Mikecz, Katalin, DeAngelis, Paul L., Haller, F. Michael, Husni, M. Elaine, Hascall, Vincent C., Calabro, Anthony
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537015/
https://ncbi.nlm.nih.gov/pubmed/23166324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.403998
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