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Advantages of AlaGln as an additive to cell culture medium: use with anti-CD20 chimeric antibody-producing POTELLIGENT™ CHO cell lines

l-alanyl-l-glutamine (AlaGln) is dipeptide that has better solubility and stability than Glutamine (Gln). In this study, we evaluated the utility of this dipeptide during culture of POTELLIGENT™ Chinese hamster ovary (CHO) cells expressing anti-CD20 chimeric antibody. Although AlaGln in the culture...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Imamoto, Yasufumi, Tanaka, Hisaya, Takahashi, Ken, Konno, Yoshinobu, Suzawa, Toshiyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536879/
https://ncbi.nlm.nih.gov/pubmed/22695857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-012-9468-8
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