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Quinacrine Impairs Enterovirus 71 RNA Replication by Preventing Binding of Polypyrimidine-Tract Binding Protein with Internal Ribosome Entry Sites

Since the 1980s, epidemics of enterovirus 71 (EV71) and other enteroviruses have occurred in Asian countries and regions, causing a wide range of human diseases. No effective therapy is available for the treatment of these infections. Internal ribosome entry sites (IRESs) are indispensable for the i...

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Detalhes bibliográficos
Main Authors: Wang, Jianmin, Du, Jiang, Wu, Zhiqiang, Jin, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536785/
https://ncbi.nlm.nih.gov/pubmed/23301007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052954
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