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PtdIns(4,5)P(2) interacts with CaM binding domains on TRPM3 N-terminus

TRPM3 has been reported to play an important role in Ca(2+) homeostasis, but its gating mechanisms and regulation via Ca(2+) are unknown. Ca(2+) binding proteins such as calmodulin (CaM) could be probable modulators of this ion channel. We have shown that this protein binds to two independent domain...

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Detalhes bibliográficos
Main Authors: Holendova, Blanka, Grycova, Lenka, Jirku, Michaela, Teisinger, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536735/
https://ncbi.nlm.nih.gov/pubmed/22989896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.22177
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