Truncated Active Human Matrix Metalloproteinase-8 Delivered by a Chimeric Adenovirus-Hepatitis B Virus Vector Ameliorates Rat Liver Cirrhosis

BACKGROUND: Liver cirrhosis is a potentially life-threatening disease caused by progressive displacement of functional hepatocytes by fibrous tissue. The underlying fibrosis is often driven by chronic infection with hepatitis B virus (HBV). Matrix metalloproteinases including MMP-8 are crucial for e...

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Detalhes bibliográficos
Principais autores: Liu, Jinxia, Cheng, Xin, Guo, Zhengrong, Wang, Zihua, Li, Dong, Kang, Fubiao, Li, Haijun, Li, Baosheng, Cao, Zhichen, Nassal, Michael, Sun, Dianxing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536652/
https://ncbi.nlm.nih.gov/pubmed/23301066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053392
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