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The Underlying Molecular and Network Level Mechanisms in the Evolution of Robustness in Gene Regulatory Networks

Gene regulatory networks show robustness to perturbations. Previous works identified robustness as an emergent property of gene network evolution but the underlying molecular mechanisms are poorly understood. We used a multi-tier modeling approach that integrates molecular sequence and structure inf...

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Detalhes bibliográficos
Main Authors: Pujato, Mario, MacCarthy, Thomas, Fiser, Andras, Bergman, Aviv
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536627/
https://ncbi.nlm.nih.gov/pubmed/23300434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002865
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