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Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

Understanding the basis for differential responses to drug therapies remains a challenge despite advances in genetics and genomics. Induced pluripotent stem cells (iPSCs) offer an unprecedented opportunity to investigate the pharmacology of disease processes in therapeutically and genetically releva...

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Detalhes bibliográficos
Main Authors: Terrenoire, Cecile, Wang, Kai, Chan Tung, Kelvin W., Chung, Wendy K., Pass, Robert H., Lu, Jonathan T., Jean, Jyh-Chang, Omari, Amel, Sampson, Kevin J., Kotton, Darrell N., Keller, Gordon, Kass, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536519/
https://ncbi.nlm.nih.gov/pubmed/23277474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210899
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