HIV Associated Neurocognitive Disorder (HAND) is Not Associated with Increased Fibrillar Amyloid Deposits Using (11)C-PiB in Middle-Aged HIV+ Participants

OBJECTIVES: Diagnostic challenges exist for differentiating HIV associated neurocognitive disorders (HAND) from symptomatic Alzheimer’s disease (AD) in HIV+ participants. Both disorders have cerebral amyloid containing plaques associated with abnormalities in amyloid beta protein 1–42 (Aβ(42)) metab...

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Main Authors: Ances, Beau M., Benzinger, Tammie L., Christensen, Jon J., Thomas, Jewell, Venkat, Rohit, Teshome, Mengesha, Aldea, Patricia, Fagan, Anne M., Holtzman, David M., Morris, John C., Clifford, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536500/
https://ncbi.nlm.nih.gov/pubmed/22232345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2011.761
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