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The C-Terminal Region of Rift Valley Fever Virus NSm Protein Targets the Protein to the Mitochondrial Outer Membrane and Exerts Antiapoptotic Function

The NSm nonstructural protein of Rift Valley fever virus (family Bunyaviridae, genus Phlebovirus) has an antiapoptotic function and affects viral pathogenesis. We found that NSm integrates into the mitochondrial outer membrane and that the protein's N terminus is exposed to the cytoplasm. The C...

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Autori principali: Terasaki, Kaori, Won, Sungyong, Makino, Shinji
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536385/
https://ncbi.nlm.nih.gov/pubmed/23097454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02192-12
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