MprAB Regulates the espA Operon in Mycobacterium tuberculosis and Modulates ESX-1 Function and Host Cytokine Response

The ESX-1 secretion system exports the immunomodulatory protein ESAT-6 and other proteins important in the pathogenesis of Mycobacterium tuberculosis. Components and substrates of ESX-1 are encoded at several loci, but the regulation of the encoding genes is only partially understood. In this study,...

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Hlavní autoři: Pang, Xiuhua, Samten, Buka, Cao, Guangxiang, Wang, Xisheng, Tvinnereim, Amy R., Chen, Xiu-Lan, Howard, Susan T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536182/
https://ncbi.nlm.nih.gov/pubmed/23104803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01067-12
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