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Identification of Burkholderia cenocepacia Strain H111 Virulence Factors Using Nonmammalian Infection Hosts

Burkholderia cenocepacia H111, a strain isolated from a cystic fibrosis patient, has been shown to effectively kill the nematode Caenorhabditis elegans. We used the C. elegans model of infection to screen a mini-Tn5 mutant library of B. cenocepacia H111 for attenuated virulence. Of the approximately...

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Détails bibliographiques
Auteurs principaux: Schwager, Stephan, Agnoli, Kirsty, Köthe, Manuela, Feldmann, Friederike, Givskov, Michael, Carlier, Aurelien, Eberl, Leo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536147/
https://ncbi.nlm.nih.gov/pubmed/23090963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00768-12
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