A Purified Capsular Polysaccharide Markedly Inhibits Inflammatory Response during Endotoxic Shock

Capsular material of the opportunistic fungus Cryptococcus neoformans is composed mainly of a polysaccharide named glucuronoxylomannan (GXM). In this study, the effects of GXM were analyzed in an in vivo experimental system of lipopolysaccharide (LPS)-induced shock. Endotoxic shock was induced in mi...

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Detalhes bibliográficos
Main Authors: Piccioni, M., Monari, C., Kenno, S., Pericolini, E., Gabrielli, E., Pietrella, D., Perito, S., Bistoni, F., Kozel, T. R., Vecchiarelli, A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536145/
https://ncbi.nlm.nih.gov/pubmed/23090956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00553-12
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