Streptococcus pneumoniae Capsular Serotype Invasiveness Correlates with the Degree of Factor H Binding and Opsonization with C3b/iC3b

Different capsular serotypes of Streptococcus pneumoniae vary markedly in their ability to cause invasive infection, but the reasons why are not known. As immunity to S. pneumoniae infection is highly complement dependent, variations in sensitivity to complement between S. pneumoniae capsular seroty...

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Main Authors: Hyams, Catherine, Trzcinski, Krzysztof, Camberlein, Emilie, Weinberger, Daniel M., Chimalapati, Suneeta, Noursadeghi, Mahdad, Lipsitch, Marc, Brown, Jeremy S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536142/
https://ncbi.nlm.nih.gov/pubmed/23147038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00862-12
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