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Beclin 1 Is Required for Starvation-Enhanced, but Not Rapamycin-Enhanced, LC3-Associated Phagocytosis of Burkholderia pseudomallei in RAW 264.7 Cells

LC3-associated phagocytosis (LAP) of Burkholderia pseudomallei by murine macrophage (RAW 264.7) cells is an intracellular innate defense mechanism. Beclin 1, a protein with several roles in autophagic processes, is known to be recruited to phagosomal membranes as a very early event in LAP. We sought...

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Detalhes bibliográficos
Main Authors: Li, Xuelei, Prescott, Mark, Adler, Ben, Boyce, John D., Devenish, Rodney J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536138/
https://ncbi.nlm.nih.gov/pubmed/23115045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00834-12
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