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Stepwise Development of a Homozygous S80P Substitution in Fks1p, Conferring Echinocandin Resistance in Candida tropicalis

Three Candida tropicalis isolates were obtained from a patient with acute lymphoblastic leukemia. The first isolate was susceptible to all drug classes, while isolates 2 and 3, obtained after 8 and 8.5 weeks of caspofungin treatment, respectively, were resistant to the three echinocandins. Multilocu...

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Détails bibliographiques
Auteurs principaux: Jensen, Rasmus Hare, Johansen, Helle Krogh, Arendrup, Maiken Cavling
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535961/
https://ncbi.nlm.nih.gov/pubmed/23089761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01193-12
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