Two Hits Are Better than One: Membrane-Active and DNA Binding-Related Double-Action Mechanism of NK-18, a Novel Antimicrobial Peptide Derived from Mammalian NK-Lysin

The extensive use and misuse of antibiotics in medicine result in the emergence of multidrug-resistant bacteria, creating an urgent need for the development of new chemotherapeutic agents. Nowadays, antimicrobial peptides are widely recognized as a class of promising candidates with activity against...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Yan, Jiexi, Wang, Kairong, Dang, Wen, Chen, Ru, Xie, Junqiu, Zhang, Bangzhi, Song, Jingjing, Wang, Rui
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2013
الموضوعات:
Mechanisms of Action: Physiological Effects
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535945/
https://ncbi.nlm.nih.gov/pubmed/23089755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01619-12
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