Deletion mutants of polyoma virus defining a nonessential region between the origin of replication and the initiation codon for early proteins.
Mutants of polyoma virus with deletions as large as 90 base pairs were isolated by selecting spontaneously arising genomes resistant to endonuclease HaeII or by treating HaeII- or BglI- cleaved linear DNAs with S1 nuclease and exonuclease III. All of the mutants were viable and, therefore, defined a...
Guardado en:
| Publicado en: | J Virol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1979
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/228076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.32.2.530-535.1979 |
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