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Role of Cytosolic Glyceraldehyde-3-Phosphate Dehydrogenase in Visceral Organ Infection by Leishmania donovani

The initial 7 steps of the glycolytic pathway from glucose to 3-phosphoglycerate are localized in the glycosomes in Leishmania, including step 6, catalyzed by the enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH). In L. donovani and L. mexicana, there exists a second GAPDH enzyme present in th...

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Bibliographic Details
Main Authors: Zhang, Wen-Wei, McCall, Laura-Isobel, Matlashewski, Greg
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535848/
https://ncbi.nlm.nih.gov/pubmed/23125352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00263-12
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