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Immunization of Mice with Formalin-Inactivated Spores from Avirulent Bacillus cereus Strains Provides Significant Protection from Challenge with Bacillus anthracis Ames

Bacillus anthracis spores are the infectious form of the organism for humans and animals. However, the approved human vaccine in the United States is derived from a vegetative culture filtrate of a toxigenic, nonencapsulated B. anthracis strain that primarily contains protective antigen (PA). Immuni...

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Bibliographic Details
Main Authors: Vergis, James M., Cote, Christopher K., Bozue, Joel, Alem, Farhang, Ventura, Christy L., Welkos, Susan L., O'Brien, Alison D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535783/
https://ncbi.nlm.nih.gov/pubmed/23114705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00550-12
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