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An Adenovirus-Based Vaccine with a Double-Stranded RNA Adjuvant Protects Mice and Ferrets against H5N1 Avian Influenza in Oral Delivery Models

An oral gene-based avian influenza vaccine would allow rapid development and simplified distribution, but efficacy has previously been difficult to achieve by the oral route. This study assessed protection against avian influenza virus challenge using a chimeric adenovirus vector expressing hemagglu...

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Sonraí Bibleagrafaíochta
Main Authors: Scallan, Ciaran D., Tingley, Debora W., Lindbloom, Jonathan D., Toomey, James S., Tucker, Sean N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535765/
https://ncbi.nlm.nih.gov/pubmed/23155123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00552-12
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