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DFI: gene feature discovery in RNA-seq experiments from multiple sources

BACKGROUND: Differential expression detection for RNA-seq experiments is often biased by normalization algorithms due to their sensitivity to parametric assumptions on the gene count distributions, extreme values of gene expression, gene length and total number of sequence reads. RESULTS: To overcom...

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Detalhes bibliográficos
Main Authors: Ozer, Hatice Gulcin, Parvin, Jeffrey D, Huang, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535702/
https://ncbi.nlm.nih.gov/pubmed/23281963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S8-S11
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