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Prefrontal cortex modulates desire and dread generated by nucleus accumbens glutamate disruption
BACKGROUND: Corticolimbic circuits, including direct projections from prefrontal cortex to nucleus accumbens (NAc), permit “top-down” control of intense motivations generated by subcortical circuits. In rats, localized disruptions of glutamate signaling within medial shell of NAc generate desire or...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535675/ https://ncbi.nlm.nih.gov/pubmed/22981656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.08.009 |
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