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Craniofacial abnormalities result from knock down of nonsyndromic clefting gene, crispld2, in zebrafish

Nonsyndromic cleft lip and palate (NSCLP), a common birth defect, affects 4000 newborns in the US each year. Previously, we described an association between CRISPLD2 and NSCLP and showed Crispld2 expression in the murine palate. These results suggested that a perturbation in CRISPLD2 activity affect...

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Détails bibliographiques
Auteurs principaux: Yuan, Qiuping, Chiquet, Brett T., DeVault, Laura, Warman, Matthew L., Nakamura, Yukio, Swindell, Eric C., Hecht, Jacqueline T.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535582/
https://ncbi.nlm.nih.gov/pubmed/22887593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22051
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