The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin’s spring elements

Titin-based passive stiffness is post-translationally regulated by several kinases that phosphorylate specific spring elements located within titin’s elastic I-band region. Whether titin is phosphorylated by calcium/calmodulin dependent protein kinase II (CaMKII), an important regulator of cardiac f...

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Détails bibliographiques
Auteurs principaux: Hidalgo, Carlos G, Chung, Charles S, Saripalli, Chandra, Methawasin, Mei, Hutchinson, Kirk R, Tsaprailis, George, Labeit, Siegfried, Mattiazzi, Alicia, Granzier, Henk L
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535572/
https://ncbi.nlm.nih.gov/pubmed/23220127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.11.012
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