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Impact on Modes of Inheritance and Relative Risks of using Extreme Sampling When Designing Genetic Association Studies
Using extreme phenotypes for association studies can improve statistical power. We study the impact of using samples with extremely high or low traits on the alternative model space, the genotype relative risks, and the genetic models in association studies. We prove the following results: when the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535545/ https://ncbi.nlm.nih.gov/pubmed/23163532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2012.00733.x |
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