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Effects of cleavage by a disintegrin and metalloproteinase with thrombospondin motifs-4 on gene expression and protein content of versican and aggrecan in the digital laminae of horses with starch gruel–induced laminitis

OBJECTIVE: To determine whether increased gene expression of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4) in laminae of horses with starch gruel– induced laminitis is accompanied by increased enzyme activity and substrate degradation. SAMPLE: Laminae from the forelimb...

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Autori principali: Wang, Le, Pawlak, Erica, Johnson, Philip J., Belknap, James K., Alfandari, Dominique, Black, Samuel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535458/
https://ncbi.nlm.nih.gov/pubmed/22738057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2460/ajvr.73.7.1047
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