Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage

Previous studies have demonstrated that aneuploidy in human embryos is surprisingly frequent with 50–80% of cleavage-stage human embryos carrying an abnormal chromosome number. Here we combine non-invasive time-lapse imaging with karyotypic reconstruction of all blastomeres in four-cell human embryo...

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Библиографические подробности
Главные авторы: Chavez, Shawn L., Loewke, Kevin E., Han, Jinnuo, Moussavi, Farshid, Colls, Pere, Munne, Santiago, Behr, Barry, Reijo Pera, Renee A.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535341/
https://ncbi.nlm.nih.gov/pubmed/23212380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2249
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