Identification of Two Novel NPM1 Mutations in Patients with Acute Myeloid Leukemia

BACKGROUND: Genetic abnormalities in adult AML are caused most frequently by somatic mutations in exon 12 of the NPM1 gene, which is observed in approximately 35% of AML patients and up to 60% of patients with cytogenetically normal AML (CN-AML). METHODS: We performed mutational analysis, including...

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Détails bibliographiques
Auteurs principaux: Jeon, Yongbum, Seo, Sang Won, Park, Seonyang, Park, Seungman, Kim, So Yeon, Ra, Eun Kyung, Park, Sung Sup, Seong, Moon-Woo
Format: Artigo
Langue:Inglês
Publié: The Korean Society for Laboratory Medicine 2013
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535198/
https://ncbi.nlm.nih.gov/pubmed/23301224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3343/alm.2013.33.1.60
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