Case Studies for Practical Food Effect Assessments across BCS/BDDCS Class Compounds using In Silico, In Vitro, and Preclinical In Vivo Data

Lignende værker

• Utility of Physiologically Based Modeling and Preclinical In Vitro/In Vivo Data to Mitigate Positive Food Effect in a BCS Class 2 Compound
  af: Xia, Binfeng, et al.
  Udgivet: (2013)
• Practical Anticipation of Human Efficacious Doses and Pharmacokinetics Using In Vitro and Preclinical In Vivo Data
  af: Heimbach, Tycho, et al.
  Udgivet: (2009)
• A Simplified PBPK Modeling Approach for Prediction of Pharmacokinetics of Four Primarily Renally Excreted and CYP3A Metabolized Compounds During Pregnancy
  af: Xia, Binfeng, et al.
  Udgivet: (2013)
• Application of Physiologically Based Absorption Modeling to Formulation Development of a Low Solubility, Low Permeability Weak Base: Mechanistic Investigation of Food Effect
  af: Zhang, Hefei, et al.
  Udgivet: (2014)
• The Effect of Excipients on the Permeability of BCS Class III Compounds and Implications for Biowaivers
  af: Parr, Alan, et al.
  Udgivet: (2015)