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In Vitro and In Vivo Evaluation of a Water-in-Oil Microemulsion System for Enhanced Peptide Intestinal Delivery

Peptide and protein drugs have become the new generation of therapeutics, yet most of them are only available as injections, and reports on oral local intestinal delivery of peptides and proteins are quite limited. The aim of this work was to develop and evaluate a water-in-oil (w/o) microemulsion s...

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Detalhes bibliográficos
Main Authors: Liu, Dongyun, Kobayashi, Taku, Russo, Steven, Li, Fengling, Plevy, Scott E., Gambling, Todd M., Carson, Johnny L., Mumper, Russell J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535102/
https://ncbi.nlm.nih.gov/pubmed/23196806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9441-7
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